Dehydrocostus Lactone ( Dehydrocostus Lactone; (-)-Dehydrocostus lactone. )

产品货号. M18596 CAS No. 477-43-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Dehydrocostus Lactone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.
产品描述

Dehydrocostus Lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ. Dehydrocostus Lactone Suppresses Proliferation of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl-JAK/STAT Signaling Pathways. Dehydrocostus Lactone Inhibits Proliferation, Antiapoptosis, and Invasion of Cervical Cancer Cells Through PI3K/Akt Signaling Pathway.
同义词

Dehydrocostus Lactone; (-)-Dehydrocostus lactone.
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

477-43-0
分子量

230.3
分子式

C15H18O2
纯度

98%
溶解度

DMSO : ≥ 62.5 mg/mL; 271.39 mM
SMILES

C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C
化学全称

(3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one

1. Dong GZ, et al. PhytOthers Res. 2015 May;29(5):680-6.

计算器

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